B – Antibody problem

Baker M. Reproducibility crisis: Blame it on the antibodies. Nature 21 May 2015;521:274-276

Antibodies are among the most commonly used tools in biological experiments, but they are littering the field with false findings. A few scientists are pushing for change and are calling for the creation of standards by which antibodies should be made, used and described. Several journals (including Nature) ask authors to make clear that antibodies used in their papers have been profiled for that particular application.