Discrepancies in reported results between trial registries and journal articles for AI clinical research

The study researches publications and clinical trial registries, including Dimensions.ai, ClinicalTrials.gov, and the EU Clinical Trials Registry, focusing on the application of AI in healthcare. 28,248 publications related to the use of AI in clinical settings were identified; 1863 publications that included a clinical trial registration ID. Authors identified discrepancies between trial registries and published results. In 53.6% of cases the authors observed selective reporting of publications; they also underline that underestimation of the incidence of adverse events is alarming.

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EClinicalMedicine. 2025 Jan 20;80:103066.  doi: 10.1016/j.eclinm.2024.103066.  PMID: 39963161;  PMCID: PMC11831125.

Recommended on behalf of EASE by Silvia Maina, Italy