B – Characteristics of randomized controlled trials

Bala MM, Akl EA, Sun X, et al. Randomized trials published in higher vs. lower impact journals differ in design, conduct, and analysis. Journal of Clinical Epidemiology 2013 (66):286-295
(doi: 10.1016/j.jclinepi.2012.10.005)

Rigorously designed and conducted randomized controlled trials (RCTs) provide high-quality evidence regarding the effects of health care interventions. This study examined and compared the study design, conduct, analysis and/or reporting of a large cohort of RCTs published in higher vs. lower impact journals. Results showed that RCTs published in higher impact journals were less prone to risk of bias.