B – Systematic reviews

Barbui C, Addis A, Amato L, et al. Can systematic reviews contribute to regulatory decisions? European Journal of Clinical Pharmacology 2017;73(4):507-509
(doi: 10.1007/s00228-016-2194-y)

Discusses the potential usefulness of systematic reviews in responding to regulatory needs. By collecting, analysing and critically appraising all relevant studies on a specific topic, they may be used by different stakeholders as a basis for making clinical and policy recommendations, including regulatory recommendations. They may simultaneously produce new findings and summarize existing knowledge, with the potential of informing regulatory decisions more pragmatically and more rapidly than other research designs.